|
KMID : 0376219820190010075
|
|
Chonnam Medical Journal
1982 Volume.19 No. 1 p.75 ~ p.89
|
|
|
Histochemical Investigations on the Rat Skeletal Muscle during Postnatal Development
|
|
|
|
|
Abstract
|
|
|
Sequential developmental changes of the rat Tibialis anterior muscle during the postnatal 8 week-period were investigated by histochemical and enzyme histochemical reactions of the muscle fibers, measuring the fiber sizes numerically.
The results were as follows.
1. Maturation of the sarcolemmal nuclei preceded sarcoplasm differentiation PAS positive granules in the sarcoplasm appeared after postnatal age of 2 weeks.
2. Myosin-ATPase reaction disclosed sequential decrease of type I fibers, from more than 80% at perinatal stage to about 40% at 8 weeks after birth. Type II A fibers were differentiated from type II B fibers after postnatal 4 weeks.
3. Histochemical properties of the muscle fibers began to differentiate after postnatal 4 weeks and thereafter became more distinctly. This suggested a close interrelationship between fiber types and kinetic demand of the skeletal muscle.
4. Type I fibers, differentiated by myosin-ATPase activities, showed more rapid growth rate than type II fibers. The difference in growth rate was more apparent from 3 weeks after birth; the long axis of type I fibers were twice as long as- that of type II fibers at 8 weeks after birth.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|